BioCryst Pharmaceuticals has announced promising growth projections for its drug ORLADEYO (berotralstat). In 2024, ORLADEYO's net revenue climbed to $437 million, reflecting a 34% increase from the previous year. This upward trend is expected to continue as the company provides guidance for 2025, anticipating net revenue between $515 million and $535 million, which would indicate growth of approximately 33-37% from 2024 figures.
Looking further into the future, BioCryst is targeting peak annual sales of $1 billion for ORLADEYO by 2029. As part of its strategy to expand market presence, the company plans to submit a new drug application for ORLADEYO in a granule form specifically designed for children under 12 years old. This initiative aims to meet significant unmet needs within this demographic. Additionally, BioCryst is actively developing new treatments, advancing clinical programs for BCX17725, targeting Netherton syndrome, and avoralstat for diabetic macular edema, with initial data anticipated by the end of the year.
Reuters reported that these strategic initiatives highlight BioCryst's commitment not only to scaling the presence of ORLADEYO but also to advancing its overall therapeutic pipeline. By pursuing these goals, the company demonstrates a focused approach in expanding its contributions to unmet medical needs and growing its market share.