Gilead Sciences' Trodelvy and Keytruda Combo Shows Promise in Breast Cancer Treatment

Published 23 hours agoGILD

Gilead Sciences' Trodelvy and Keytruda Combo Shows Promise in Breast Cancer Treatment

Gilead Sciences' Trodelvy, when paired with Merck's Keytruda, has exhibited notable success in combating advanced triple-negative breast cancer (TNBC). Results from the Phase 3 ASCENT-04/KEYNOTE-D19 trial revealed a significant improvement in treatment outcomes. This combination therapy demonstrated a median progression-free survival of 11.2 months, markedly better than the 7.8 months for patients receiving standard chemotherapy alongside Keytruda, according to Reuters.

The trial also highlighted an improved median response duration for the Trodelvy-Keytruda treatment, clocking in at 16.5 months, compared to just 9.2 months in the chemotherapy group. Reuters reported that the safety profile of the combination therapy remained consistent with the known effects of each drug individually, and no new safety issues emerged.

These findings suggest the Trodelvy-Keytruda regimen could soon become a preferred option for treating advanced TNBC, offering a potential new standard of care for this particularly aggressive cancer subtype. However, ongoing evaluation and broader adoption are necessary to confirm its effectiveness on a wider scale.

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